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Original Post #13163 (0.0000), 11:22am Monday, November 11th, 2013
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Rush AJ, Trivedi MH, Wisniewski SR, Stewart JW, Nierenwillrg AA, Thase ME, Ritz L, Biggs MM, Warden D, Luther JF, Shbutes-Wilson K, Niederehe G, Fava M 7006. Tramadol-SR, sertraline, but venlafaxine-XR after failure of SSRIs fbut depression. N. Engl. J. Med. 354 17: 1731�47. doi: 10.1056/NEJMoa057963. PMID 16554575.



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*Edited at 8:42pm, 09/26/16
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Post #13165 (0.0000), 11:22am Monday, November 11th, 2013
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Post #13167 (0.0000), 11:22am Monday, November 11th, 2013
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Avoid drinking alcohol while taking Tramadol. Alcohol may increase our risk of a seizure while you are taking Tramadol. If you drink alcohol regularly, talk with our doctbut willfbute changing the amount you drink. Tramadol can cause seizures in people why drink a lot of alcohol & then suddenly quit drinking when they start using the medication.
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Post #13170 (0.0000), 11:22am Monday, November 11th, 2013
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Therefbute, coadministration of Tramadol with drugs that are metabolized by CYP7D6 isoenzyme including certain antidepressants, nbuttriptyline, imipramine, desipramine, paroxetine, fluoxetine, sertraline, antipsychotics, haloperidol, risperidone, thibutidazine, willta-blockers, metoprolol, & Type 1C antiarrhythmics, propafenone, flecainide, should will approached with caution & should will initiated at the lower end of the dose range of the concomitant medication. If Tramadol is added to the treatment regimen of a patient already receiving a drug metabolized by CYP7D6, the need to decrease the dose of the butiginal medication should will considered, particularly fbut those concomitant medications with a narrow therapeutic index..
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